When investigating microbial communities, some of the main questions include, which microorganisms are present and how abundant are they? Shotgun metagenomics sequencing is a powerful tool for investigating bio-diversity of microbial communities.
Common challenges include unwanted signals from host DNA which can reduce the sensitivity at which the microorganisms can be detected. In addition, large data volumes and the complex data structure of metagenomics data further complicate computational analysis.
The new tool Taxonomic Profiling offers taxonomic analysis of Whole metagenome shotgun sequencing data. Start metagenome analysis on day one with two preconfigured workflows for data QC and taxonomic profiling. Easy to use Statistical tools enable comparison of microbial communities across many samples.
Using the right reference data is crucial for accurate taxonomic profiling. But bigger is not always better – database size and content affect computer resource requirements and specificity.
The new tool Create Microbial Reference Database is designed to overcome these common challenges in metagenome analysis.
From discovery to routine use
Managing reference data is crucial for translating a discovery application into routine use. For exploring the microbial diversity in novel sample types use a comprehensive database. For highest precision and faster turn-around time in routine use, simply remove irrelevant taxa from the reference database.
The new tool Create Microbial Reference Database allows users to build customised reference genome databases for use in taxonomic profiling and microbial isolate typing.
The latest release features two new preconfigured and easy-to-use Workflows that combine the most important steps of taxonomic microbiome profiling: Data QC and removal of contamination, taxonomic profiling of one or many samples, and downstream statistical analysis.
© QIAGEN 2017. All rights reserved - Trademarks & Disclaimers