Many recent advances in epigenetics research can be attributed to the technology-enabled ability to survey epigenetic modifications on a genome-wide scale. CLC Genomics Workbench offers a comprehensive set of tools to detect and compare epigenetic markers:
Cytosine methylation is probably the best-studied form of epigenetic regulation of gene expression. The Bisulfite Sequencing plugin included in CLC Genomics Workbench offers an all-in-one solution to common problems scientists face when studying cytosine methylation data.
Recent improvements promise deeper insights into transcriptional regulation, even in the absence of control samples. Transcription factor ChIP-Seq exposes defined peak regions characteristic of transcription factor binding sites throughout the whole genome. All made accessible through our tried and trusted intuitive graphical user interface.
Acetylation of histones is an important epigenetic adaptation associated with chromatin decondensation and up-, or down-regulated gene expression. The Histone ChIP-Seq plugin included in CLC Genomics Workbench detects evidence for Histone acetylation marks.Request a trial
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