The legacy of experience

Unravel epigenetic adaptations
with state-of-the-art tools

Many recent advances in epigenetics research can be attributed to the technology-enabled ability to survey epigenetic modifications on a genome-wide scale. CLC Genomics Workbench offers a comprehensive set of tools to detect and compare epigenetic markers:

Detect DNA Methylation through Bisulfite Sequencing

Cytosine methylation is probably the best-studied form of epigenetic regulation of gene expression. The Bisulfite Sequencing plugin included in CLC Genomics Workbench offers an all-in-one solution to common problems scientists face when studying cytosine methylation data.

Transcriptionfactor ChIP-Seq

Recent improvements promise deeper insights into transcriptional regulation, even in the absence of control samples. Transcription factor ChIP-Seq exposes defined peak regions characteristic of transcription factor binding sites throughout the whole genome. All made accessible through our tried and trusted intuitive graphical user interface.

Histone ChiP-Seq plugin

Acetylation of histones is an important epigenetic adaptation associated with chromatin decondensation and up-, or down-regulated gene expression. The Histone ChIP-Seq plugin included in CLC Genomics Workbench detects evidence for Histone acetylation marks.

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