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The recent explosion in the use of next-generation sequencing in the study of human disease

has led to an exponential rise in the number of publications on the subject.


With the burden of manual curation dramatically increasing, extracting valuable and up-to-date

variant information is now a daunting task.


Transform how you find answers with

QIAGEN Clinical Insight

Transparent, evidence-sourced NGS variant calling, interpretation and reporting



QCI automates variant classification with full transparency to the supporting evidence sourced

from the QIAGEN Knowledge Base–the largest, most-up-to-date clinical database

with over 16 million biological findings and over 1 million processed human samples.

QCI Interpret

Precision medicine for any disease, any assay,
on your platform


Enable comprehensive clinical NGS analysis and reporting

QCI automatically incorporates actionability criteria supporting tier classifications of the AMP/ASCO/CAP and ACMG/AMP Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer.

Integrate diverse content sources for variant interpretation and reporting

The QIAGEN Knowledge Base stands as an interconnected and interdependent network of structured data built by MD and PhD certified content curation specialists. With one click, you receive information on the variant’s characteristics, active clinical trial registries, and available drug therapies.

Accelerate time from sequence to report

Implement a full workflow for variant calling through pre-configured and expandable NGS secondary data analysis pipelines that take you from FASTQ to VCF faster. QCI Analyze Universal is the companion product to QCI Interpret that allows you to confidently identify variants from your NGS tests.




Offering the highest level of interpretation transparency currently available in the market, QCI Interpret displays every piece of supporting evidence included in the interpretation process.

The software is connected to the QIAGEN Knowledge Base, the industry’s largest, most-up-to-date clinical database with over 16 million biological findings.

Pulling data from clinical trials, case studies, peer-reviewed literature, drug labels, external databases, professional guidelines, and the direct experience of interpreting over 1 MILLION human samples, the QIAGEN Knowledge Base is unrivalled in clinical breadth and depth.

Feature Applications



Try QCI Interpret

Request your free, no obligation, demonstration of QCI Interpret today.



*QIAGEN Clinical Insight (QCI) is an evidence-based decision support software intended as an aid in the interpretation of variants observed in genomic sequencing data. The software evaluates genomic variants in the context of published biomedical literature, professional association guidelines, publicly available databases and annotations, drug labels, and clinical-trials. Based on this evaluation, the software proposes a classification to aid in the interpretation of observed variants. The software is NOT intended as a primary diagnostic tool by physicians or to be used as a substitute for professional healthcare advice. Each laboratory is responsible for ensuring compliance with applicable international, national, and local clinical laboratory regulations and other specific accreditations requirements.