Release date: 2018-12-06
NCBI API keys for E-utilities can now be entered under Preferences | Advanced | NCBI API Key. This may be of particular interest where multiple machines with CLC Workbenches installed use the same IP address. If an NCBI API key is provided, it is used when running the following tools: Search for Reads in SRA, Search for Sequences at NCBI, Search for PDB Structures at NCBI
The Search for Sequences in Uniprot tool now uses the HTTPS protocol.
If you are concerned about these changes, please contact the QIAGEN Bioinformatics team ([email protected]).
Release date: 2018-03-14
Implemented the 3' HGVS compliance rule for c. annotation of variants:
- When doing c. annotations (DNA-level HGVS) we annotate insertions that really are duplications as such.
- For c. annotations we furthermore fulfill the 3' rule for insertions, deletions and duplications.
- When determining amino acid changes, the 3' rule is applied to the DNA change first. This may shift a variant in or out of the coding region, and that will affect whether or not we consider it as an amino acid change.
The 3' rule for p. annotations were previously fulfilled and are not affected by this fix.
If you are concerned about the proposed changes, please contact our Support team ([email protected]).
Release date: 2017-11-21