Short read lengths and repetitive genomic regions often result in fragmented de novo assemblies. To improve results and convert contigs into high quality assemblies a complex process referred to as genome finishing is needed.
CLC Genome Finishing Module is an add-on to CLC Genomics Workbench, designed to accelerate and simplify genome finishing, and make this process accessible to life scientist without deep understanding of bioinformatics.
Improve your de novo assembly using Join Contigs. Leverage in one step a combination of finishing methods. Scaffold contigs using paired reads or long read (like PacBio) data, and carry out automatic alignment of contigs to each other or to a closely related genome.
Assemble reference genomes faster. PacBio’s single molecule real-time sequencing platform generates data fast. Is data analysis now your bottleneck? We bring you the fastest and simplest way to error-correct and assemble PacBio long reads into high quality assemblies with CLC Genome Finishing Module.
Utility for most commonly sequenced genome types
The module was designed for finishing smaller genomes, and is ideal for assembling microbes, eukaryotic parasites, or fungi. Automated tools for scaffolding or contig joining also improve results for larger genome assemblies, but manual editing is not feasible for plant or animal genomes.