See a presentation of our new epigenomics features and find out how to fully benefit from the advances of CLC Genomics Workbench for detecting DNA methylation through bisulfite sequencing, transcription factor ChIP-Seq, and histone ChIP-Seq.
CLC Genomics Workbench gives deeper insights into transcriptional regulation, and epigenetic adaptations. Dedicated ChIP-Seq tools reveal coverage peaks characteristic of Transcription Factor (TF) or Histone binding. A plugin links to TRANSFAC for prediction of transcription factor binding sites. And you can explore DNA methylation with our Bisulfite-Sequencing tools.
The ability to analyze our bisulfite sequencing data within the CLC environment is a real advantage for us. We’ve analyzed whole genome, genome wide oligonulcotide capture, and amplicon bisulfite data sets. Being able to get base specific quantitation of CG and non-CG methylation in a strand specific manner all within one program and with an intuitive GUI has been a hit with the lab and is much simpler than our previous work flows.
Willard M. Freeman, Ph.D.
Prof. Freeman leads the Targeted DNA Methylation & Mitochondrial Heteroplasmy Core offering
DNA methylation analysis and other services to researchers at the University of Oklahoma Health Sciences Center.
Other affiliations: Donald W. Reynolds Chair in Aging Research, Associate Professor of Physiology, Adjunct Associate Professor of Geriatric Medicine, Member, Harold Hamm Diabetes Institute, Associate Member, Stephenson Cancer Center, University of Oklahoma Health Sciences Center.