Discovery
Thursday, August 20, 2015

Microbial genome assembly made fast and easy

Assembling gold standard reference genomes for microbial pathogens has become fast and easy. We’re proud to bring you a new feature allowing rapid error correction and assembly of PacBio data.

The latest version of CLC Genome Finishing Module introduces tools for error-correction and de novo assembly of raw PacBio reads. High quality assemblies can be generated in a fraction of the time that is needed by leading alternatives.

CLC Genome Finishing Module consumes less than 10 percent of the memory used by alternative solutions, while completing the assembly faster. The Module runs on all major operating systems, and fully integrates into the widely used CLC Genomics Workbench and CLC Genomics Server solutions. The included preconfigured workflow makes it extremely user-friendly.

Benchmarking
We compared the performance of the industry standard HGAP1 when run on a high performance computer to the performance of the workflow “PacBio De Novo Assembly Pipeline” included in CLC Genome Finishing Module. Please note that our PacBio De Novo Assembly Pipeline was run on a standard laptop for this comparison.

1Chin et al. (2013), Nature Methods, 10(6), 563–569


Not convinced yet? Try it out

 

Benchmark: PacBio error correction and de novo assembly by organism and PacBio chemistry

Benchmark: PacBio error correction and de novo assembly by organism and PacBio chemistry

 

 

 


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